Profile

Code

Indications

Tests

Sample

ACTH stim

ADR1

Confirm diagnosis of Cushings syndrome

Take baseline serum for cortisol assay
Dogs: inject IV/IM 250ug synthetic ACTH (Synacthen), resample 2hr
Cats: inject IV/IM 125ug Synacthen, resample 1hr and 3hr

serum x2
serum x3

Low dose
DEX

ADR2

Confirm diagnosis of Cushings syndrome

Take baseline serum for cortisol assay
Dogs: inject IV 0.015mg/kg dexamethasone, resample 3hr and 8hr
Cats: inject IV 0.1mg/kg dexamethasone, resample 6hr and 8hr

Hi dose DEX

ADR3

Confirm diagnosis of Cushings syndrome

Take baseline serum for cortisol assay
Dogs: inject IV 0.1mg/kg dexamethasone, resample 3hr and 8hr

serum x3

TRH
stim

THY1

Confirm
hypothyroidism

Take baseline serum for canine T4
Dogs: administer TRH IV slowly over 1 min at dose of 100ug (1-5kg),
200ug (5-30kg), 300ug (>30kg) and resample in 4-6 hrs.
Cats: 100ug TRH IV slowly over 1 min and resample in 4-6hrs

Bile acid
stim

BA1

Confirm hepatic disease or porto-caval shunt

Take serum after fasting for 8-12 hours
Feed a normal meal and resample in 2 hours
(Single post-prandial sample added to baseline small animal profile)

serum x2
serum x1